September 13, 2015
Dr. Blaise Aguirre is an American psychiatrist who specializes in BPD. He runs a residential treatment centre for adolescent girls at the McLean Hospital in Boston, Massachusetts. Normal insulin secretion from the beta cells in the pancreas must be impaired for a patient to develop type 2 diabetes. Acute exposure of the pancreatic beta cells to both high glucose concentrations and saturated free fatty acid stored and released from fat tissue increases the release of insulin, but chronic exposure results in desensitization and suppression of insulin secretion. This loop between insulin release and glucose in the blood eventually leads to a state of insulin resistance, where muscle, fat, and liver cells do not respond appropriately to insulin.
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